Aziridine

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Application
It is used in medicine, synthesis of compounds, textile chemicals, adhesives, binders, petroleum refining chemicals, fuels, lubricants, coating resins, varnishes, lacquers, agricultural chemicals, cosmetics, ion exchange resins, and photographic chemicals, and as a surfactant
Description
Aziridine is an organic compound consisting of the three-membered heterocycle (CH2)2NH. It is a colorless, toxic, volatile liquid that is of significant practical interest. Aziridine was discovered in 1888 by the chemist Siegmund Gabriel. Its derivatives, also referred to as aziridines, are of broader interest in medicinal chemistry.
Aziridine is produced industrially from aminoethanol via two related routes. The Nippon Shokubai process requires an oxide catalyst and high temperatures to effect the dehydration. In the Wenker synthesis, the aminoethanol is converted to the sulfate ester, which undergoes base-induced sulfate elimination. Older methods entailed amination of 1,2-dichloroethane and cyclization of 2-chloroethylamine.
Aziridine forms a wide variety of polymeric derivatives, known as polyethylenimines. These and related species are useful crosslinking agents and precursors for coatings.
Aziridine is highly toxic with an LD50 of 14 mg (oral, rats). It is a skin irritant. As an alkylating agent, it is also a mutagen. It is reactive toward DNA, potentially relevant to its mutagenicity. Aziridine containing compounds also appear to be similarly dangerous.

Product Properties

Set 1

CAS
151-56-4
Chemical Formula
C2H5N
Appearance/State
Colorless Oily Liquid
Density/Bulk density
g/L
832.1
Molecular Weight
43.1 g/mol
Melting point
°C
- 77.9
Boiling point
°C
56
Freezing point
°C
- 71.5
Flash Point
°C
- 11
Odor
Pungent, ammonia-like

Packaging

Pricing

Unit
-
Currency
-
Value
-

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General Info

Listing Type
Product
Published
Oct 29, 2021
Last Edited
Oct 29, 2021
Categories
Chemicals
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